diff --git a/setup-scripts/README.md b/setup-scripts/README.md
index cd011524..335fc3c1 100644
--- a/setup-scripts/README.md
+++ b/setup-scripts/README.md
@@ -55,10 +55,28 @@ done so.
 
 To enable the service: `systemctl --user enable siad.service`
 
+### Running 2 siad instances
+In some cases, portal operators may want to run 2 `siad` nodes on the same
+server. One node to prioritize downloads and one to prioritze uploads The
+scripts here also do the initial setup for a 2nd `siad` instance running as a
+systemd service `siad-upload.service` in the `~/siad-upload/` directory with
+environment variables in `sia-upload.env`. You must fill out the correct values
+for those environment variables.
+
+The `bashrc` file in this repository  also provides an alias `siac-upload` that
+loads the correct environment variables and sets the correct ports to interact
+with the 2nd `siad` node.
+
+`siac` is used to operate node 1, and `siac-upload` is used to operate node 2.
+
+To enable the 2nd service: `systemctl --user enable siad-upload.service`
+
 ### Useful Commands
 
 To start the service: `systemctl --user start siad`
+
 To stop it: `systemctl --user stop siad`
+
 To check the status of it: `systemctl --user status siad`
 
 To check standard err/standard out: `journalctl --user-unit siad`