diff --git a/api/middleware/s5.go b/api/middleware/s5.go
index f8be175..c082d5a 100644
--- a/api/middleware/s5.go
+++ b/api/middleware/s5.go
@@ -121,8 +121,14 @@ func BuildS5TusApi(portal interfaces.Portal) jape.Handler {
 		})
 	})
 
+	stripPrefix := func(h jape.Handler) jape.Handler {
+		return jape.Adapt(func(h http.Handler) http.Handler {
+			return http.StripPrefix("/s5/tus/upload/", h)
+		})(h)
+	}
+
 	// Apply the middlewares to the tusJapeHandler
-	tusHandler := ApplyMiddlewares(tusJapeHandler, authMiddlewareFunc, protocolMiddleware)
+	tusHandler := ApplyMiddlewares(tusJapeHandler, stripPrefix, authMiddlewareFunc, protocolMiddleware)
 
 	return tusHandler
 }